Advanced Eye Care Conference London, UK | June 06-07, 2019 Abird's eye view for improved diagnosis

In closed-angle glaucoma, the optic nerve is damaged because the aqueous fluid in the eye does not drain properly. This is because the gap between the cornea and the iris, known as the anterior chamber angle, where fluid normally flows through the eye, has narrowed significantly or become blocked. The resulting build-up of pressure within the eye, which can happen rapidly, can cause irreversible blindness.

Current diagnosis of closed-angle glaucoma involves analyzing anterior segment optical coherence tomography' (AS-OCT) images, which are cross-sectional pictures of the eye's anterior chambers. However, manual comparison of AS-OCT images, particularly those taken using different systems, takes considerable time and expertise.

Although the eye structure shown in every AS-OCT image is different, local regions within each eye are similar. When our algorithm receives a new eye image, it searches the annotated dataset for 'best-fit' images that are the closest match in terms of eye structure and anterior chamber angle, before transferring the labels from these selected library images to the new image.

The algorithm then applies a smoothing technique to refine the structural labeling and ensure it is accurate for each unique eye shape. This allows very precise clinical measurements of the anterior chamber angle and other diagnostic features.

During tests, the algorithm was able to segment and measure one AS-OCT image in ten seconds, providing a potentially invaluable tool for clinicians.

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